Furane

From WikiMD's Wellness Encyclopedia


Furane, also known as furan, is a heterocyclic compound consisting of a five-membered aromatic ring with four carbon atoms and one oxygen atom. It is a colorless, flammable, highly volatile liquid with a boiling point close to room temperature. Furane is used as a starting material for other specialty chemicals.

Structure and Properties[edit | edit source]

Furane has the molecular formula C4H4O. The structure of furane consists of a planar ring with alternating double bonds, making it an aromatic compound. The oxygen atom in the ring contributes to the aromaticity by donating a pair of electrons to the π-system.

Synthesis[edit | edit source]

Furane can be synthesized through several methods, including the decarbonylation of furfural and the Paal-Knorr synthesis. The Paal-Knorr synthesis involves the cyclization of 1,4-diketones in the presence of an acid catalyst.

Applications[edit | edit source]

Furane is used in the production of tetrahydrofuran (THF), which is an important solvent in the polymer industry. It is also a precursor to pyrrole and other heterocyclic compounds. Additionally, furane derivatives are used in the manufacture of pharmaceuticals, agrochemicals, and as intermediates in organic synthesis.

Safety[edit | edit source]

Furane is highly flammable and should be handled with care. It is also a potential carcinogen, and exposure should be minimized. Proper safety protocols, including the use of personal protective equipment (PPE) and adequate ventilation, should be followed when working with furane.

Related Compounds[edit | edit source]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD