Gastrulation

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Gastrulation is a significant stage in the embryonic development of multicellular organisms. During this phase, the blastula is reorganized into a structure known as the gastrula. This process forms the three primary germ layers of the embryo: the ectoderm, mesoderm, and endoderm.

Overview[edit | edit source]

Gastrulation varies in different species. In amphibians and birds, it involves a series of cell movements and invaginations. In mammals, gastrulation involves the formation of a blastocyst. Despite these differences, the end result across all species is the formation of the three germ layers.

Process[edit | edit source]

The process of gastrulation can be divided into several steps:

  1. Formation of the Primitive Streak: The primitive streak is a structure that forms in the blastula during the early stages of embryonic development. It is the site where cells will ingress and form the mesoderm and endoderm.
  2. Ingression of Cells at the Primitive Streak: Cells at the primitive streak undergo changes in shape and migrate inwards. This migration results in the formation of the mesoderm and endoderm.
  3. Formation of the Notochord: The notochord forms from mesoderm cells that have migrated along the primitive streak. The notochord plays a crucial role in the development of the nervous system.
  4. Neurulation: This is the process by which the neural plate, a region of ectodermal cells, develops into the neural tube. This tube will eventually form the brain and spinal cord.

Germ Layers[edit | edit source]

The three germ layers formed during gastrulation are:

  1. Ectoderm: This outermost layer develops into the skin, brain, and the nervous system.
  2. Mesoderm: This middle layer develops into the muscles, bones, and circulatory system.
  3. Endoderm: This innermost layer develops into the digestive system, lungs, and other internal organs.

See Also[edit | edit source]

References[edit | edit source]

Gastrulation Resources
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Contributors: Prab R. Tumpati, MD