Genetic map
Genetic map or linkage map is a type of genetic analysis that shows the position of genes and genetic markers relative to each other on a chromosome. The greater the frequency that two gene loci are inherited together, the smaller the distance between them on the map.
Overview[edit | edit source]
A genetic map is not a physical map (such as a chromosome map). While physical maps measure the physical distance between gene loci, genetic maps are based on the genetic linkage information. The units of a genetic map are centimorgans (cM), named after the American geneticist Thomas Hunt Morgan.
Construction of a Genetic Map[edit | edit source]
The construction of a genetic map involves the following steps:
- Collection of genetic markers: These are genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. They can be described as variations which can be observed.
- Genotyping: The process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and comparing it to another individual's sequence or a reference sequence.
- Analysis of recombination frequency: The frequency of recombination is the number of recombinant offspring divided by the total number of offspring. It is used to determine the distance between two genes on a genetic map.
Uses of Genetic Maps[edit | edit source]
Genetic maps are used in many different ways:
- They can help scientists understand and treat diseases by identifying genes that cause or contribute to diseases.
- They can be used in plant and animal breeding to help select for traits of interest.
- They can help scientists understand the evolution and migration of different species.
See Also[edit | edit source]
References[edit | edit source]
Genetic map Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Admin, Prab R. Tumpati, MD