Human herpesvirus 8

Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is a type of herpesvirus that is linked with Kaposi's sarcoma, a type of cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat, in lymph nodes, or in other organs.

Overview

HHV-8 is one of the eight known viruses of the herpesviridae family that cause human disease. It is also associated with two rare diseases, primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD).

Transmission

The virus is believed to be transmitted through saliva and sexual contact, but can also be spread through organ transplantation and blood transfusions.

Symptoms

Most people infected with HHV-8 do not show any symptoms. However, people with weakened immune systems, such as those with HIV/AIDS, may develop Kaposi's sarcoma, PEL, or MCD.

Diagnosis

Diagnosis of HHV-8 is often made by identifying the virus in a sample of tissue taken from a lesion. Blood tests can also be used to detect antibodies to the virus.

Treatment

There is currently no cure for HHV-8, but antiviral medications can help control the virus and manage symptoms.

Prevention

Prevention strategies include practicing safe sex and avoiding sharing items that may contain saliva.

See also

• Herpesvirus
• Kaposi's sarcoma
• Primary effusion lymphoma
• Multicentric Castleman's disease
• HIV/AIDS

References

Human herpesvirus 8 Resources
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