Interleukin 17F
Interleukin 17F (IL-17F) is a protein that in humans is encoded by the IL17F gene. It is a member of the interleukin 17 family of cytokines, which are signaling molecules that play a crucial role in the body's immune response.
Function[edit | edit source]
IL-17F is produced by T cells and is involved in several immune responses. It stimulates the production of other cytokines such as interleukin 6, interleukin 8, and granulocyte-macrophage colony-stimulating factor, as well as prostaglandins and nitric oxide. IL-17F can also regulate cartilage matrix turnover and inhibit the formation of endothelial tubes.
Clinical significance[edit | edit source]
Alterations in the function of IL-17F have been associated with several diseases. For example, it has been implicated in the pathogenesis of rheumatoid arthritis, asthma, and psoriasis. In addition, mutations in the IL17F gene have been linked to susceptibility to chronic mucocutaneous candidiasis.
References[edit | edit source]
External links[edit | edit source]
| Interleukin 17F Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
