Tunica intima

From WikiMD's Wellnesspedia

(Redirected from Internal coat)

Tunica intima or intima is the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flowing through the artery or vein.

Structure[edit | edit source]

The tunica intima is the innermost layer of a blood vessel, surrounded by the tunica media and the tunica adventitia. It is composed of a layer of simple squamous endothelium cells supported by a 'subendothelial layer' of collagen. The endothelial cells sit on a basement membrane, which is a layer of proteins and other molecules that provide support and anchorage for the cells.

Function[edit | edit source]

The tunica intima has several important functions. It provides a smooth surface for the flow of blood, reducing friction and preventing blood clot formation. The endothelial cells also produce substances that control vasodilation and vasoconstriction, helping to regulate blood pressure and blood flow. In addition, they play a role in inflammation and immune response.

Clinical significance[edit | edit source]

Damage to the tunica intima can lead to a number of medical conditions. For example, atherosclerosis involves the build-up of fatty deposits in the tunica intima, which can restrict blood flow and lead to heart disease or stroke. Inflammation of the tunica intima, known as vasculitis, can also cause serious health problems.

See also[edit | edit source]

References[edit | edit source]


Tunica intima Resources

Find a healthcare provider anywhere in the world quickly and easily!

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Admin, Prab R. Tumpati, MD