Intima

Intima is the innermost layer of a blood vessel, lying in direct contact with the blood as it flows through the vessel. It is composed of a single layer of simple squamous endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood in the lumen of the vessel.

Structure

The intima is the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood in the lumen. This layer is much thinner in veins than in arteries.

Function

The intima provides a smooth surface for the flow of blood and regulates the movement of white blood cells and platelets to and from the bloodstream. It also plays a key role in the process of atherosclerosis, the buildup of fatty deposits in the artery walls.

Clinical significance

Damage to the intima can lead to atherosclerosis, a disease in which plaque builds up inside your arteries. This can lead to serious problems, including heart attack, stroke, or even death.

See also

• Endothelium
• Artery
• Vein
• Atherosclerosis

References

Intima Resources
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