Killer T cell

Killer T cell

Killer T cells, also known as cytotoxic T cells or CD8+ T cells, are a type of T cell that play an integral role in the immune system's response to infected or cancerous cells. They are named for their ability to kill cells that are infected with viruses or other pathogens, or are otherwise damaged or dysfunctional.

Function

Killer T cells are activated when their T cell receptor (TCR) binds to a specific antigen on the surface of an infected cell or tumor cell. This binding process is highly specific, and each T cell is programmed to recognize a specific antigen. Once activated, the killer T cell releases cytotoxic substances that cause the target cell to undergo apoptosis, or programmed cell death.

Development

Killer T cells develop in the thymus, an organ located in the chest. Here, they undergo a process of maturation and selection to ensure that they can effectively recognize and respond to antigens. Once mature, they are released into the bloodstream and lymphatic system, where they patrol the body for signs of infection or disease.

Role in disease

Killer T cells play a crucial role in the body's defense against disease. They are particularly important in the immune response to viral infections, where they can directly kill infected cells and prevent the virus from spreading. However, they can also contribute to autoimmune diseases, where they mistakenly attack the body's own cells.

See also

• Immune system
• T cell
• Antigen
• Apoptosis
• Autoimmune disease

Killer T cell Resources
Latest articles Most recent articles Ongoing trials	Wikipedia