Large granular lymphocyte
Large Granular Lymphocyte (LGL) is a type of white blood cell that is part of the immune system. These cells are characterized by their large size and the presence of granules in their cytoplasm. They play a crucial role in the body's defense against infection and disease.
Function[edit | edit source]
LGLs are primarily involved in the immune response to viral infections. They are capable of killing infected cells directly, and also produce cytokines, which are chemical messengers that help to coordinate the immune response.
Types[edit | edit source]
There are two main types of LGLs: Natural Killer (NK) cells and T-cells. NK cells are part of the innate immune system and can kill infected cells without prior exposure to the pathogen. T-cells, on the other hand, are part of the adaptive immune system and require prior exposure to the pathogen to mount an effective response.
Disorders[edit | edit source]
Disorders of LGLs can lead to a variety of medical conditions. For example, Large granular lymphocytic leukemia is a rare type of cancer that involves the proliferation of LGLs. On the other hand, a decrease in the number of LGLs can lead to an increased susceptibility to infections.
See also[edit | edit source]
| Large granular lymphocyte Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
