Meiotic
Meiotic Cell Division
Meiotic cell division, commonly referred to as meiosis, is a specialized form of cell division that reduces the chromosome number by half, resulting in the production of haploid gametes or spores. This process is essential for sexual reproduction in eukaryotic organisms, including animals, plants, and fungi. Meiosis ensures genetic diversity through recombination and independent assortment of chromosomes.
Overview[edit | edit source]
Meiosis consists of two sequential stages: Meiosis I and Meiosis II. Each stage is further divided into distinct phases: prophase, metaphase, anaphase, and telophase. The entire process results in four non-identical daughter cells, each with half the number of chromosomes of the original cell.
Meiosis I[edit | edit source]
Meiosis I is known as the reductional division because it reduces the chromosome number by half. It includes the following phases:
Prophase I[edit | edit source]
Prophase I is the longest phase of meiosis and is characterized by the pairing of homologous chromosomes, a process known as synapsis. This phase is further divided into five sub-stages: leptotene, zygotene, pachytene, diplotene, and diakinesis. During pachytene, crossing over occurs, where homologous chromosomes exchange genetic material, leading to genetic recombination.
Metaphase I[edit | edit source]
In metaphase I, homologous chromosome pairs align at the metaphase plate. The orientation of each pair is random, contributing to genetic variation through independent assortment.
Anaphase I[edit | edit source]
During anaphase I, the homologous chromosomes are pulled apart to opposite poles of the cell. Unlike mitosis, sister chromatids remain attached at their centromeres.
Telophase I and Cytokinesis[edit | edit source]
Telophase I involves the reformation of the nuclear envelope around each set of chromosomes, followed by cytokinesis, which divides the cytoplasm, resulting in two haploid cells.
Meiosis II[edit | edit source]
Meiosis II resembles a mitotic division and is known as the equational division. It separates the sister chromatids of each chromosome.
Prophase II[edit | edit source]
In prophase II, the nuclear envelope breaks down, and the spindle apparatus forms in each haploid cell.
Metaphase II[edit | edit source]
Chromosomes align at the metaphase plate, similar to metaphase in mitosis.
Anaphase II[edit | edit source]
Sister chromatids are finally separated and pulled to opposite poles of the cell.
Telophase II and Cytokinesis[edit | edit source]
Nuclear envelopes reform around each set of chromosomes, and cytokinesis occurs, resulting in four genetically distinct haploid cells.
Significance of Meiosis[edit | edit source]
Meiosis is crucial for maintaining the stability of a species' chromosome number across generations. It introduces genetic variation through recombination and independent assortment, which are key drivers of evolution.
Also see[edit | edit source]
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Contributors: Prab R. Tumpati, MD