Neurokinin

Neurokinin is a family of neuropeptides that are known for their role in neurotransmission. They are primarily involved in the regulation of pain and inflammation responses in the body. The three main types of neurokinins are substance P, neurokinin A, and neurokinin B.

Substance P

Substance P is the most well-known and extensively studied neurokinin. It is involved in the transmission of pain signals from peripheral receptors to the central nervous system. Substance P is also involved in the regulation of mood disorders, anxiety, stress, and depression.

Neurokinin A

Neurokinin A is another important member of the neurokinin family. It is involved in a variety of physiological processes, including the regulation of blood pressure, smooth muscle contraction, and the release of certain hormones.

Neurokinin B

Neurokinin B is the third member of the neurokinin family. It is primarily involved in the regulation of reproductive functions. Neurokinin B is also known to play a role in the regulation of body temperature and the sleep-wake cycle.

Role in Disease

Neurokinins have been implicated in a variety of diseases, including migraine, asthma, irritable bowel syndrome, and rheumatoid arthritis. They are also involved in the pathophysiology of depression and anxiety disorders.

Treatment

Due to their involvement in disease, neurokinins have become a target for therapeutic intervention. Several drugs that target neurokinins, known as neurokinin receptor antagonists, have been developed for the treatment of conditions such as depression, anxiety, and chronic pain.

See Also

• Neuropeptide
• Neurotransmission
• Pain
• Inflammation
• Substance P
• Neurokinin A
• Neurokinin B
• Migraine
• Asthma
• Irritable bowel syndrome
• Rheumatoid arthritis
• Depression
• Anxiety disorders
• Neurokinin receptor antagonists

Neurokinin Resources
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