Pancreatic enzyme
Pancreatic Enzymes are a group of digestive enzymes produced and secreted by the pancreas. These enzymes are essential for the digestion and absorption of most nutrients in the small intestine.
Function[edit | edit source]
Pancreatic enzymes play a crucial role in the digestive system. They help break down fats, proteins, and carbohydrates, making it possible for the body to absorb nutrients from the foods we eat. The three main types of pancreatic enzymes are amylase, protease, and lipase.
Amylase[edit | edit source]
Amylase is responsible for breaking down carbohydrates into simple sugars, which can be easily absorbed by the body.
Protease[edit | edit source]
Protease enzymes break down proteins into amino acids. These amino acids are then used by the body for various functions, including tissue repair and energy production.
Lipase[edit | edit source]
Lipase is responsible for breaking down fats into fatty acids and glycerol. These components are then absorbed by the body and used for energy.
Clinical Significance[edit | edit source]
A deficiency in pancreatic enzymes can lead to malabsorption syndromes such as pancreatic insufficiency, cystic fibrosis, and chronic pancreatitis. These conditions can result in malnutrition and weight loss due to the body's inability to absorb nutrients effectively.
Pancreatic enzyme replacement therapy (PERT) is a treatment option for individuals with pancreatic enzyme deficiency. This therapy involves taking pancreatic enzyme supplements to aid in digestion and nutrient absorption.
See Also[edit | edit source]
- Digestive enzyme
- Exocrine pancreatic insufficiency
- Pancreatic cancer
- Pancreatic enzyme replacement therapy
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Contributors: Prab R. Tumpati, MD