Primitive gut
Primitive gut refers to the early stage of the embryonic development in vertebrates, including humans, during which the embryo's initial digestive tube is formed. This structure is foundational in the development of the digestive system, and its formation marks a critical phase in embryogenesis. The primitive gut is established during the process of gastrulation, where the three primary germ layers (ectoderm, mesoderm, and endoderm) are formed. The gut itself originates from the endoderm, the innermost layer, which rolls into a tube that will eventually differentiate into the various components of the digestive system.
Formation[edit | edit source]
The formation of the primitive gut begins with the creation of the primitive streak on the surface of the embryo. This streak forms the initial axis of the embryo and marks the site where cells begin to migrate inwards, a process known as invagination. These migrating cells form the endoderm and mesoderm, with the endoderm eventually displacing the yolk sac cells to become the lining of the primitive gut.
Following invagination, the endoderm-lined cavity extends along the length of the embryo, developing into the foregut, midgut, and hindgut. These regions are precursors to major organs and structures of the digestive system:
- The foregut gives rise to the pharynx, esophagus, stomach, and the initial part of the duodenum, as well as respiratory structures like the lungs.
- The midgut forms the remainder of the duodenum, the jejunum, ileum, cecum, and the beginning of the colon.
- The hindgut develops into the rest of the colon, the rectum, and the upper part of the anal canal.
Clinical Significance[edit | edit source]
Abnormalities in the development of the primitive gut can lead to congenital defects such as esophageal atresia, intestinal atresia, and anorectal malformations. Understanding the embryological processes involved in the formation of the primitive gut is crucial for diagnosing and managing these conditions.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
