Edrophonium

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Edrophonium is a drug that is used in the diagnosis of myasthenia gravis, a neuromuscular disease. It is also used to reverse the effects of certain types of anesthesia.

Mechanism of Action[edit | edit source]

Edrophonium works by inhibiting the action of acetylcholinesterase, an enzyme that breaks down acetylcholine in the body. This leads to an increase in the concentration of acetylcholine at neuromuscular junctions, improving muscle strength and tone.

Uses[edit | edit source]

Edrophonium is primarily used in the diagnosis of myasthenia gravis. It is also used to reverse the effects of non-depolarizing muscle relaxants after surgery.

Side Effects[edit | edit source]

Common side effects of edrophonium include nausea, vomiting, diarrhea, abdominal pain, and sweating. In rare cases, it can cause bradycardia, hypotension, and bronchospasm.

Contraindications[edit | edit source]

Edrophonium is contraindicated in patients with known hypersensitivity to the drug. It should also be used with caution in patients with asthma, cardiac disease, or peptic ulcer disease.

Interactions[edit | edit source]

Edrophonium may interact with other drugs, including anticholinergic drugs, beta-blockers, and calcium channel blockers.

See Also[edit | edit source]

Edrophonium Resources
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