Aranidipine

Aranidipine is a calcium channel blocker used primarily for the treatment of hypertension. It is also known by its brand name, Sapresta.

Etymology

The name "Aranidipine" is derived from the drug's chemical structure. It is a dihydropyridine calcium channel blocker, and its name reflects this. The prefix "Ara-" is derived from the Latin word for "spider," referencing the drug's ability to "weave" its way into the calcium channels of the heart and blood vessels. The "-dipine" suffix is common among calcium channel blockers and is derived from the term "dihydropyridine."

Pharmacology

Aranidipine works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. It achieves this by binding to the L-type calcium channel and blocking its function. This results in vasodilation and a reduction in peripheral vascular resistance, which in turn lowers blood pressure.

Clinical Use

Aranidipine is primarily used in the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. The drug is typically administered orally, and its effects can be seen within a few hours of administration.

Side Effects

Like other calcium channel blockers, Aranidipine can cause a range of side effects. These may include dizziness, flushing, headache, and edema. In rare cases, it may cause more serious side effects such as heart palpitations or chest pain.

Related Terms

• Calcium channel blocker
• Hypertension
• L-type calcium channel
• Vasodilation
• Peripheral vascular resistance

Aranidipine Resources
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