TMC6
TMC6 is a gene that in humans is encoded by the TMC6 protein. It is also known as EVER1 and is associated with the condition Epidermodysplasia verruciformis.
Function[edit | edit source]
The TMC6 gene provides instructions for making a protein that is found in the outer layer of the skin (the epidermis). Although the exact function of this protein is unknown, it likely plays a role in the growth and development of skin cells. The TMC6 protein is also thought to be involved in the body's immune response to certain types of human papillomavirus (HPV).
Clinical significance[edit | edit source]
Mutations in the TMC6 gene have been associated with Epidermodysplasia verruciformis, a rare skin disorder. This condition is characterized by an increased susceptibility to specific types of HPV, including those that are a common cause of skin warts. People with Epidermodysplasia verruciformis are also at a high risk of developing non-melanoma skin cancer.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- GeneReviews/NCBI/NIH/UW entry on Epidermodysplasia Verruciformis
- OMIM entries on Epidermodysplasia Verruciformis
| TMC6 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
