Trichloromethane

From WikiMD's Food, Medicine & Wellness Encyclopedia

Trichloromethane (also known as chloroform) is a colorless, heavy, sweet-smelling, non-flammable liquid that is produced on a large scale as a precursor to PVC. It is also a precursor to various refrigerants. It is one of the four chloromethanes and a trihalomethane.

History[edit | edit source]

Trichloromethane was first prepared in 1831 by the chemist Justus von Liebig, in the haloform reaction. The haloform reaction can also occur inadvertently in domestic settings. Bleaching with hypochlorite generates halogenated compounds in side reactions; chloroform is the main byproduct.

Production[edit | edit source]

Trichloromethane is produced industrially through the chlorination of methane and chloromethane. In the home, it can be produced by the haloform reaction between bleach and acetone.

Uses[edit | edit source]

Trichloromethane has been used as a powerful anesthetic, a precursor to PVC, and a solvent for fats, oils, rubber, and resins. It is also used in the production of refrigerants.

Health effects[edit | edit source]

Exposure to trichloromethane can cause a range of health effects, including liver and kidney damage, and it is considered a possible human carcinogen.

See also[edit | edit source]

Trichloromethane Resources
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Contributors: Prab R. Tumpati, MD