Turnover number
(Redirected from Turn over number)
Turnover number (also known as kcat) is a concept in enzyme kinetics. It represents the maximum number of chemical conversions of substrate molecules per second that a single catalytic site will execute for a given enzyme concentration enzyme concentration under saturating conditions of the substrate.
Definition[edit | edit source]
The turnover number is defined as the number of molecules of substrate that an enzyme can convert into product per enzyme molecule per second. It is a measure of the catalytic activity of the enzyme, and is often used to compare the efficiencies of different enzymes, or different substrates of the same enzyme.
Calculation[edit | edit source]
The turnover number is calculated by dividing the maximum rate of reaction (Vmax) by the concentration of the enzyme ([E]). This gives the units of the turnover number as s-1, which means "per second".
Factors affecting turnover number[edit | edit source]
The turnover number of an enzyme can be affected by a number of factors, including the concentration of the substrate, the temperature and pH of the reaction, and the presence of any inhibitors or activators.
See also[edit | edit source]
References[edit | edit source]
Turnover number Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD