Α-Linolenic acid

From WikiMD's Food, Medicine & Wellness Encyclopedia

Α-Linolenic acid (ALA) is an omega-3 fatty acid that is essential for human health but cannot be synthesized by the human body. It is a polyunsaturated fatty acid (PUFA) and is considered crucial for maintaining a healthy heart, brain function, and promoting general health. ALA is found in many plant sources, including flaxseed, chia seeds, hemp seeds, walnuts, and soybeans.

Sources of Α-Linolenic Acid[edit | edit source]

The primary sources of ALA are plant oils, with flaxseed oil being one of the richest sources. Other significant sources include:

Health Benefits[edit | edit source]

Α-Linolenic acid is associated with numerous health benefits:

  • Cardiovascular Health: Consumption of ALA has been linked to a reduced risk of cardiovascular disease. It helps in lowering blood pressure, reducing artery plaque, and improving overall heart health.
  • Anti-inflammatory Effects: ALA has anti-inflammatory properties that may help in reducing the risk of chronic diseases.
  • Brain Function: Omega-3 fatty acids, including ALA, are essential for brain health and cognitive function.
  • Immune System Support: ALA can help in boosting the immune system.

Metabolism[edit | edit source]

In the human body, ALA undergoes a series of enzymatic conversions to longer-chain omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). However, this conversion process is inefficient in humans, leading to recommendations that individuals also consume direct sources of EPA and DHA.

Dietary Recommendations[edit | edit source]

The recommended dietary allowance (RDA) for ALA varies by age, sex, and life stage. Health organizations typically recommend that ALA constitute a certain percentage of dietary energy, usually around 0.6% to 1.2% of total energy intake.

Considerations[edit | edit source]

While ALA is beneficial, it is important to balance the intake of omega-3 and omega-6 fatty acids in the diet, as an imbalance can lead to health issues. Additionally, individuals with specific health conditions should consult with healthcare professionals before making significant changes to their omega-3 fatty acid consumption.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD