Β-Zearalanol

Β-Zearalanol (also known as β-Zearalanol or Zeranol) is a nonsteroidal estrogen that is derived from the mycotoxin zearalenone. It is primarily used in veterinary medicine as a growth promoter in livestock, particularly in the beef industry.

History

Β-Zearalanol was first identified in the 1960s as a metabolite of the Fusarium fungus, which produces the mycotoxin zearalenone. It was later synthesized and developed for use in veterinary medicine.

Use in Veterinary Medicine

In veterinary medicine, β-Zearalanol is used as a growth promoter in livestock. It is typically administered as an implant in the ear of the animal, where it slowly releases the compound over a period of several months. The use of β-Zearalanol has been shown to increase weight gain and improve feed efficiency in cattle.

Health and Safety Concerns

There have been concerns about the potential health effects of β-Zearalanol, particularly in relation to its estrogenic activity. Some studies have suggested that exposure to β-Zearalanol may have adverse effects on reproductive health. However, the evidence is not conclusive and further research is needed.

Regulation

The use of β-Zearalanol is regulated in many countries. In the European Union, it is banned for use in food-producing animals. However, it is approved for use in the United States and other countries.

See Also

• Zearalenone
• Growth promoter
• Veterinary medicine