Taleranol

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A synthetic estrogen used in veterinary medicine

Taleranol

Taleranol




Chemical nomenclature
IUPAC name (3S,8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol


























Taleranol is a synthetic estrogen that is primarily used in veterinary medicine. It is a nonsteroidal estrogen that belongs to the class of compounds known as mycoestrogens, which are naturally occurring estrogens produced by fungi.

Chemical structure and properties[edit]

Structural formula of Taleranol

Taleranol is a derivative of the mycoestrogen zearalenone, which is produced by several species of Fusarium fungi. The chemical structure of taleranol is characterized by a cyclopenta[a]phenanthrene skeleton, which is typical of many steroidal estrogens, although taleranol itself is nonsteroidal.

Mechanism of action[edit]

Taleranol exerts its effects by binding to estrogen receptors in target tissues. This binding mimics the action of endogenous estrogens, leading to the activation of estrogen-responsive genes. The primary physiological effects of taleranol are similar to those of natural estrogens, including the promotion of growth and development of female secondary sexual characteristics and the regulation of the menstrual cycle.

Uses in veterinary medicine[edit]

In veterinary practice, taleranol is used as a growth promoter in livestock, particularly in cattle. It is administered to improve feed efficiency and promote weight gain. The use of taleranol in animals is regulated to ensure that residues do not remain in meat products intended for human consumption.

Safety and regulation[edit]

The use of taleranol, like other growth-promoting agents, is subject to strict regulatory controls. In some countries, the use of synthetic estrogens in food-producing animals is banned or restricted due to concerns about potential health risks to humans. Monitoring programs are in place to detect residues of taleranol and other similar compounds in meat products.

Related pages[edit]

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