From WikiMD's Food, Medicine & Wellness Encyclopedia

(–)-Arctigenin is a phytochemical found in certain plants of the Asteraceae family, such as the Greater Burdock (Arctium lappa) and Saussurea Involucrata. It is a lignan, a type of phenolic compound, and has been studied for its potential health benefits.

Chemical Structure[edit | edit source]

(–)-Arctigenin is a dibenzylbutyrolactone lignan. Its chemical structure consists of two phenyl groups (benzene rings) connected by a prop-2-ene diol chain (butyrolactone). The (–) in its name refers to its optical activity, indicating that it is a left-handed or levorotatory isomer.

Sources[edit | edit source]

The primary natural sources of (–)-Arctigenin are plants in the Asteraceae family. The most well-known of these is the Greater Burdock, a plant native to Europe and Asia that has been used in traditional medicine for centuries. Another source is Saussurea Involucrata, a rare plant found in the mountains of China and Russia.

Potential Health Benefits[edit | edit source]

Research into the potential health benefits of (–)-Arctigenin is ongoing. Studies have suggested that it may have anti-inflammatory, anti-viral, and anti-cancer properties. However, these findings are preliminary and more research is needed to confirm them and understand how (–)-Arctigenin works in the human body.

Safety and Side Effects[edit | edit source]

As with any supplement, it is important to use (–)-Arctigenin responsibly. While it is generally considered safe when used in moderation, excessive consumption can lead to side effects such as nausea and diarrhea. Always consult with a healthcare provider before starting any new supplement regimen.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD