RTI-55
(Redirected from (-)-2β-Carbomethoxy-3β-(4-iodophenyl)tropane)
RTI-55 (also known as 2β-carbomethoxy-3β-(4-iodophenyl)tropane or β-CIT) is a synthetic compound of the phenyltropane group. It is used in scientific research and has been studied for potential use in medical imaging. RTI-55 binds to the dopamine transporter (DAT) and the serotonin transporter (SERT), and to a lesser extent the norepinephrine transporter (NET).
Etymology[edit | edit source]
The name "RTI-55" is derived from the initials of the Research Triangle Institute, which first synthesized the compound, and the number 55, which is the order in which it was synthesized.
Pharmacology[edit | edit source]
RTI-55 is a potent inhibitor of the dopamine transporter (DAT), the serotonin transporter (SERT), and the norepinephrine transporter (NET). It has been used in scientific research to map the distribution of these transporters in the brain. RTI-55 is radiolabeled with iodine-123 for this purpose.
Medical Imaging[edit | edit source]
RTI-55 has been studied for potential use in medical imaging. It can be used to label the dopamine transporter in the brain, which may be useful in the diagnosis of Parkinson's disease and other disorders of the dopaminergic system.
Related Compounds[edit | edit source]
RTI-55 is a member of the phenyltropane group of compounds, which also includes RTI-31, RTI-32, RTI-51, and RTI-121. These compounds are all potent inhibitors of the dopamine transporter.
See Also[edit | edit source]
 | |
|---|---|
 |
 |
RTI-55[edit | edit source]
Phenyltropane 11e - RTI-55
RTI-55 Syntheses
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
