RTI-121

RTI-121 (also known as iodine-123-2β-carbomethoxy-3β-(4-iodophenyl)tropane) is a synthetic radioligand that is used in scientific research. It is a phenyltropane based compound that was developed in the 1990s. RTI-121 is primarily used in the study of the dopamine transporter, due to its high affinity for this protein.

Chemistry

RTI-121 is a phenyltropane based compound. It is structurally similar to cocaine, but has a much higher affinity for the dopamine transporter. This makes it a useful tool in the study of this protein. The iodine-123 isotope used in RTI-121 is a gamma emitter, which allows it to be used in SPECT imaging.

Uses

RTI-121 is primarily used in scientific research. It is used in SPECT imaging to study the dopamine transporter. This can be useful in the study of diseases such as Parkinson's disease and drug addiction, which are associated with changes in the function of the dopamine transporter.

See also

• RTI-55
• RTI-83
• RTI-371

References

RTI-121 Resources
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