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N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate

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N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate

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Brief summary - N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate
N,O-Dimethyl-4β-(2-naphthyl)piperidine-3β-carboxylate (DMNPC) is a piperidine based stimulant drug which is synthesised from arecoline. It is similar to nocaine in chemical structure, and has two and a half times more activity than cocaine as a dopamine reuptake inhibitor. However it is also a potent serotonin reuptake inhibitor, with similar affinity to fluoxetine.It is a structural isomer of another potent dopamine reuptake inhibitor, HDMP-28. Clearly it is not just the SS enantiomer of the title compound that is an active MAT inhibitor.

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