(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid[edit | edit source]
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid is a chemical compound that acts as a selective antagonist of the GABAC receptor. It is commonly abbreviated as TPMPA.
Chemical Structure[edit | edit source]
The chemical structure of (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid consists of a tetrahydropyridine ring attached to a methylphosphinic acid group. The presence of the phosphinic acid moiety is crucial for its activity as a GABAC receptor antagonist.
Mechanism of Action[edit | edit source]
TPMPA functions by selectively inhibiting the GABAC receptors, which are a subclass of GABA receptors. These receptors are ligand-gated ion channels that mediate inhibitory neurotransmission in the central nervous system. By blocking these receptors, TPMPA can modulate the inhibitory effects of GABA, potentially affecting various neurological processes.
Applications in Research[edit | edit source]
Due to its selective antagonistic properties, TPMPA is used in neuroscience research to study the role of GABAC receptors in the brain. It helps in understanding the physiological and pathological roles of these receptors in various neurological conditions.
Related Compounds[edit | edit source]
TPMPA is part of a broader class of compounds known as GABA receptor antagonists. Other related compounds include bicuculline and picrotoxin, which target different subtypes of GABA receptors.
See Also[edit | edit source]
Related Pages[edit | edit source]
Structure of (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
Transform your life with W8MD's budget GLP1 injections from $125
W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.
Why choose W8MD?
- Comprehensive care with FDA-approved weight loss medications including:
- loss injections in NYC both generic and brand names:
- weight loss medications including Phentermine, Qsymia, Diethylpropion etc.
- Accept most insurances for visits or discounted self pay cost.
- Generic weight loss injections starting from just $125.00 for the starting dose
- In person weight loss NYC and telemedicine medical weight loss options in New York city available
- Budget GLP1 weight loss injections in NYC starting from $125.00 biweekly with insurance!
Book Your Appointment
Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
