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1,1-diethoxyethane 200.svg

1,1-Diethoxyethane, also known as acetaldehyde diethyl acetal, is a chemical compound with the formula C_6H_14O_2. This organic compound is categorized under the class of acetals, which are important in both organic chemistry and industrial applications. 1,1-Diethoxyethane is a clear, colorless liquid with a mild, pleasant odor, commonly used as a solvent and an intermediate in the synthesis of other compounds.

Properties[edit | edit source]

1,1-Diethoxyethane has a molecular weight of 118.17 g/mol and boils at approximately 102-104 °C. It is relatively stable and soluble in most organic solvents, but it is less soluble in water. Its stability and solubility make it a versatile solvent for various chemical reactions and processes.

Synthesis[edit | edit source]

The synthesis of 1,1-Diethoxyethane typically involves the Fischer-Speier esterification, where acetaldehyde reacts with ethanol in the presence of an acid catalyst. This reaction not only demonstrates the formation of acetals from aldehydes but also highlights the reversible nature of acetal formation, which is crucial in protecting carbonyl groups in organic synthesis.

Applications[edit | edit source]

1,1-Diethoxyethane is widely used in the chemical industry as a solvent for resins, varnishes, and organic syntheses. Its ability to dissolve a wide range of chemical compounds without reacting with them makes it valuable in the formulation of paints, coatings, and adhesives. Additionally, it serves as an intermediate in the synthesis of pharmaceuticals, where it is used to protect aldehyde groups from unwanted reactions during complex synthesis processes.

Safety[edit | edit source]

Like many organic solvents, 1,1-Diethoxyethane poses certain health risks. Inhalation or ingestion can lead to irritation of the respiratory tract, central nervous system depression, and other acute health effects. Proper handling, storage, and disposal procedures should be followed to minimize exposure and environmental impact.

Environmental Impact[edit | edit source]

The environmental impact of 1,1-Diethoxyethane is primarily associated with its volatility and potential to contribute to air pollution. It is important to monitor its release into the environment and adhere to regulations aimed at reducing solvent emissions.


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Contributors: Prab R. Tumpati, MD