From WikiMD's Food, Medicine & Wellness Encyclopedia

1,2-Didehydro-3-oxo-THCO is a synthetic cannabinoid that is a derivative of THC, the primary psychoactive component of cannabis. It is a potent agonist of the CB1 receptor, which is primarily found in the brain and is responsible for the psychoactive effects of cannabis.

Chemistry[edit | edit source]

1,2-Didehydro-3-oxo-THCO is a synthetic cannabinoid, meaning it is not naturally occurring but is instead created in a laboratory. It is a derivative of THC, meaning it is structurally similar to THC but has been chemically modified. The "1,2-Didehydro" part of its name refers to the removal of two hydrogen atoms from the 1 and 2 positions of the THC molecule, and the "3-oxo" part refers to the addition of a double-bonded oxygen atom at the 3 position.

Pharmacology[edit | edit source]

As a synthetic cannabinoid, 1,2-Didehydro-3-oxo-THCO acts as an agonist at the CB1 receptor, meaning it binds to this receptor and activates it. The CB1 receptor is primarily found in the brain and is responsible for the psychoactive effects of cannabis. By activating this receptor, 1,2-Didehydro-3-oxo-THCO produces effects similar to those of THC, including euphoria, altered perception, and increased appetite.

Legal Status[edit | edit source]

The legal status of 1,2-Didehydro-3-oxo-THCO varies by country and region. In some places, it is classified as a controlled substance due to its similarity to THC. In others, it is legal to possess and use. It is important to check local laws before possessing or using this substance.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD