1-Benzyl-4-methylpiperazine

1-Benzyl-4-methylpiperazine (BZP) is a synthetic compound that belongs to the piperazine class of chemicals. It is known for its stimulant properties and has been used recreationally as a designer drug. BZP is structurally similar to amphetamines and has been used as a substitute for MDMA (ecstasy) in some contexts.

Chemical Structure and Properties

1-Benzyl-4-methylpiperazine is a derivative of piperazine, a chemical compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions. The chemical formula for BZP is C₁₁H₁₆N₂, and its molecular weight is 176.26 g/mol.

The structure of BZP includes a benzyl group attached to the nitrogen atom at the 1-position of the piperazine ring, and a methyl group attached to the nitrogen atom at the 4-position. This configuration contributes to its psychoactive effects.

Pharmacology

BZP acts as a central nervous system stimulant. It increases the release of dopamine and serotonin in the brain, leading to effects similar to those of amphetamines. Users report feelings of euphoria, increased energy, and enhanced sociability. However, BZP can also cause adverse effects such as anxiety, insomnia, and increased heart rate.

Legal Status

The legal status of BZP varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. For example, BZP is classified as a Schedule I substance in the United States, meaning it is illegal to manufacture, distribute, or possess.

Health Risks

The use of BZP can pose significant health risks. Acute effects may include tachycardia, hypertension, hyperthermia, and seizures. Chronic use can lead to psychological dependence and other long-term health issues. Due to these risks, BZP is not considered safe for human consumption.

History and Use

BZP was initially synthesized in the 1970s as a potential antidepressant, but it was never marketed for this purpose. In the late 1990s and early 2000s, BZP gained popularity as a recreational drug, often sold in "party pills" or "legal highs." Its use has declined in recent years due to increased regulation and awareness of its risks.

Also see

• Piperazine
• Amphetamine
• MDMA
• Designer drug
• Controlled substance