Piperazine

Piperazine is a type of organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists in two forms, as a free base and as a salt. The piperazine family of drugs contain a core piperazine structure.

History

Piperazine was first introduced in the mid-1950s. It was initially used as an anthelmintic to treat worm infestations in both humans and animals.

Medical uses

Piperazine is used primarily in the treatment of parasitic worm infestations. Piperazines are also used in the manufacture of plastics, resins, pesticides, brake fluid and other industrial materials.

Side effects

Common side effects of piperazine use include nausea, headache, dizziness, and abdominal pain. In rare cases, severe allergic reactions may occur.

Pharmacology

Piperazine works by paralyzing the parasites, which allows them to be easily expelled from the body. The drug is effective against a variety of parasitic worms, including roundworms, pinworms, and hookworms.

See also

• Anthelmintic
• Parasitic worm
• Organic compound

References

Piperazine Resources
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