From WikiMD's Food, Medicine & Wellness Encyclopedia


1-Dotriacontanol is a fatty alcohol with the chemical formula C32H66O. It is a long-chain primary alcohol that is of interest in various scientific and industrial fields due to its unique properties and applications. This compound is part of a broader class of waxes that are found in nature and can also be synthesized through various chemical processes.

Properties[edit | edit source]

1-Dotriacontanol is characterized by its high molecular weight and solid state at room temperature. It has a melting point that is significantly higher than that of many other fatty alcohols, which makes it useful in applications requiring materials with a stable phase at higher temperatures. Its solubility in water is extremely low due to its long hydrocarbon chain, but it is soluble in nonpolar organic solvents such as hexane, chloroform, and ethanol.

Sources[edit | edit source]

Naturally, 1-Dotriacontanol can be found in small amounts in the wax of certain plant leaves and in the cuticles of some insects. The extraction from natural sources is often not economically viable for large-scale applications, leading to a preference for synthetic production methods.

Synthesis[edit | edit source]

The synthesis of 1-Dotriacontanol typically involves the elongation of shorter chain fatty alcohols or the reduction of the corresponding fatty acid or ester. These processes can be achieved through various chemical reactions, including hydrogenation and Grignard reactions, depending on the starting materials and desired purity of the final product.

Applications[edit | edit source]

1-Dotriacontanol finds applications in a variety of fields due to its chemical stability and physical properties. In the cosmetics industry, it is used as an ingredient in skin creams, lotions, and other personal care products for its emollient properties. In the industrial sector, it serves as a lubricant, protective coating, and a component in the manufacture of certain types of plastics and rubbers. Additionally, its role in research, particularly in studies related to lipid membranes and long-chain alcohol interactions with biological systems, is of ongoing interest.

Safety and Toxicology[edit | edit source]

As with many chemical compounds, the safety of 1-Dotriacontanol depends on its concentration and the manner of exposure. It is generally considered to have low toxicity, but appropriate safety measures should be taken to avoid inhalation, ingestion, or prolonged skin contact, especially in industrial settings.

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Contributors: Prab R. Tumpati, MD