16α-Hydroxy-DHEA sulfate

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16α-Hydroxy-DHEA_sulfate.svg



16α-Hydroxy-DHEA sulfate is a chemical compound that is a sulfate ester of 16α-Hydroxy-DHEA. It is a metabolite of dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal glands.

Biochemistry[edit | edit source]

16α-Hydroxy-DHEA sulfate is formed from the hydroxylation of DHEA at the 16α position, followed by sulfation. This process is catalyzed by specific enzymes in the body. The compound is involved in various biological processes and can be converted into other steroids.

Function[edit | edit source]

The exact function of 16α-Hydroxy-DHEA sulfate in the body is not fully understood. However, it is believed to play a role in the biosynthesis of other important steroid hormones, including estrogens and androgens.

Clinical Significance[edit | edit source]

Abnormal levels of 16α-Hydroxy-DHEA sulfate may be associated with certain endocrine disorders. It is sometimes measured in clinical tests to assess adrenal function and hormonal imbalances.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD