Ketosteroid

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Ketosteroids are a type of steroid that contains a keto group. They are produced in the adrenal glands and are involved in a variety of biological processes, including the regulation of metabolism and immune response.

Structure and Function[edit | edit source]

Ketosteroids have a similar structure to other steroids, with a four-ring core structure. The presence of a keto group at a specific position on the steroid molecule distinguishes ketosteroids from other types of steroids. This keto group plays a crucial role in the biological activity of ketosteroids.

Ketosteroids are involved in a variety of biological processes. They play a key role in the regulation of metabolism, helping to control the rate at which the body uses energy. They also play a role in the immune response, helping to regulate the body's response to infection and disease.

Production and Regulation[edit | edit source]

Ketosteroids are produced in the adrenal glands, which are small glands located on top of the kidneys. The production of ketosteroids is regulated by a complex network of hormones and signaling pathways. This ensures that the body produces the right amount of ketosteroids at the right time.

Clinical Significance[edit | edit source]

Abnormal levels of ketosteroids can be indicative of a variety of medical conditions. For example, elevated levels of ketosteroids can be a sign of Cushing's syndrome, a condition characterized by excessive cortisol production. On the other hand, low levels of ketosteroids can be a sign of Addison's disease, a condition characterized by insufficient cortisol production.

Measurement of ketosteroids in the urine can be used as a diagnostic tool in the evaluation of adrenal function. This can help in the diagnosis of conditions such as Cushing's syndrome and Addison's disease.

See Also[edit | edit source]

Ketosteroid Resources
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Contributors: Prab R. Tumpati, MD