2-Iodomelatonin

2-Iodomelatonin is a radioactive tracer that is used in the medical field, specifically in the study of melatonin receptors. It is a derivative of melatonin, a hormone that regulates sleep and wakefulness.

Overview

2-Iodomelatonin is a potent ligand for melatonin receptors, which are found in various tissues throughout the body. These receptors play a crucial role in the regulation of the circadian rhythm, which is the body's internal clock that dictates sleep-wake cycles.

The compound is labeled with iodine-125, a radioactive isotope of iodine. This allows it to be detected and tracked in the body, making it a valuable tool for studying the distribution and function of melatonin receptors.

Uses

In medical research, 2-Iodomelatonin is used to map the location of melatonin receptors in the body. This can help researchers understand how these receptors contribute to various physiological processes, including sleep regulation, immune function, and mood regulation.

In addition, 2-Iodomelatonin can be used in the development of new drugs that target melatonin receptors. By studying how this compound interacts with these receptors, researchers can gain insights into how potential drugs might behave.

Safety

As a radioactive compound, 2-Iodomelatonin must be handled with care to prevent unnecessary exposure to radiation. However, the amount of radiation emitted by this compound is relatively low, and it is quickly eliminated from the body, minimizing the risk of long-term radiation exposure.

See also

• Melatonin
• Melatonin receptor
• Iodine-125
• Radioligand

2-Iodomelatonin Resources
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