3-(p-Fluorobenzoyloxy)tropane

3-(p-Fluorobenzoyloxy)tropane is a tropane derivative that acts as a potent monoamine transporter inhibitor and stimulant drug. It is structurally similar to cocaine, but the orientation of the fluorine atom at the para position of the benzoyl group is different.

Chemistry

3-(p-Fluorobenzoyloxy)tropane is a synthetic compound of the tropane class. Tropanes are a class of bicyclic alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. This compound is structurally similar to cocaine, which is also a tropane derivative, but differs in the orientation of the fluorine atom at the para position of the benzoyl group.

Pharmacology

As a monoamine transporter inhibitor, 3-(p-Fluorobenzoyloxy)tropane blocks the reuptake of the neurotransmitters dopamine, norepinephrine, and serotonin from the synapse into the pre-synaptic neuron. This results in an increase in the extracellular concentrations of these neurotransmitters and therefore an increase in neurotransmission.

The compound is also a stimulant drug. Stimulants increase the activity of the central nervous system and the body, leading to increased alertness, attention, and energy.

Medical Use

Currently, there are no approved medical uses for 3-(p-Fluorobenzoyloxy)tropane. However, due to its structural similarity to cocaine, it has been studied for its potential use in the treatment of cocaine addiction. Further research is needed to determine the safety and efficacy of this compound for this use.

See Also

• Cocaine
• Tropane
• Monoamine transporter
• Stimulant