4'-Fluoro-α-pyrrolidinooctanophenone

Synthetic stimulant of the cathinone class

4'-Fluoro-α-pyrrolidinooctanophenone (also known as 4F-α-POP) is a synthetic stimulant of the cathinone class. It is chemically related to other synthetic cathinones such as α-Pyrrolidinohexiophenone (α-PHP) and α-Pyrrolidinoheptanophenone (α-PHP). This compound has been used as a designer drug and is known for its stimulant effects.

Chemical Structure and Properties

Chemical structure of 4'-Fluoro-α-pyrrolidinooctanophenone

4'-Fluoro-α-pyrrolidinooctanophenone is characterized by the presence of a fluorine atom at the para position of the phenyl ring, a pyrrolidine ring, and an octanophenone backbone. The molecular formula is C₁₈H₂₆FNO, and it has a molar mass of 291.40 g/mol.

The presence of the fluorine atom is believed to influence the compound's pharmacological activity, potentially increasing its potency compared to non-fluorinated analogs. The pyrrolidine ring is a common feature in many synthetic cathinones, contributing to their stimulant properties.

Pharmacology

4'-Fluoro-α-pyrrolidinooctanophenone acts as a central nervous system stimulant. It is thought to exert its effects by increasing the levels of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This is achieved through the inhibition of their reuptake into presynaptic neurons, similar to the mechanism of action of other cathinones and amphetamines.

The stimulant effects of 4F-α-POP can lead to increased alertness, euphoria, and enhanced physical performance. However, these effects are accompanied by potential adverse effects such as anxiety, paranoia, and cardiovascular issues.

Legal Status

The legal status of 4'-Fluoro-α-pyrrolidinooctanophenone varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is often included in legislation targeting synthetic cathinones and other novel psychoactive substances.

Health Risks and Toxicity

The use of 4F-α-POP is associated with several health risks. Acute toxicity can result in symptoms such as tachycardia, hypertension, hyperthermia, and seizures. Chronic use may lead to addiction, psychosis, and other long-term health issues.

Due to the lack of clinical studies, the full extent of its toxicity and long-term effects is not well understood. Users are at risk of experiencing unpredictable and potentially severe adverse effects.

Related pages

• Cathinone
• Synthetic cathinones
• Designer drug
• Stimulant