4-CAB
4-CAB (4-chloroandrost-4-ene-3β,17β-diol), also known as 4-chloroandrostenediol or 4-chloro-DHEA, is a synthetic androstenediol that was first described in a 2009 patent application and is sold as a dietary supplement. It is a chlorinated derivative of androstenediol and is also related to other chlorinated steroids, such as mibolerone and clostebol.
Chemistry[edit | edit source]
4-CAB, also known as 4-chloroandrost-4-ene-3β,17β-diol, is a synthetic androstane steroid and a derivative of dihydrotestosterone (DHT). It is more specifically a derivative of androstenediol (androst-5-ene-3β,17β-diol), with a chlorine atom at the C4 position. Other chlorinated steroids include clostebol (4-chlorotestosterone; 4-chloroandrost-4-en-17β-ol-3-one), mibolerone (7α,17α-dimethyl-4-chloro-DHT), and gestrinone (17α-ethynyl-18-methyl-19-nor-4,9,11-trienolone).
Pharmacology[edit | edit source]
As a derivative of androstenediol, 4-CAB is a prohormone of 4-chlorotestosterone. It is also a prohormone of 4-chloro-DHT, which is more potent as an agonist of the androgen receptor than is testosterone.
Society and culture[edit | edit source]
4-CAB is marketed as a prohormone in the United States, where it is sold over-the-counter as a dietary supplement.
See also[edit | edit source]
- List of androgens/anabolic steroids
- List of androgen esters
- List of investigational sex-hormonal agents
References[edit | edit source]
4-CAB Resources | |
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Contributors: Prab R. Tumpati, MD