4-Methyl-α-ethylaminopentiophenone

From WikiMD's Food, Medicine & Wellness Encyclopedia

4-Methyl-α-ethylaminopentiophenone (also known as 4-MEAP and 4-Methylpentedrone) is a stimulant of the cathinone class that has been sold online as a designer drug. It is a higher homologue of 4-Methylmethcathinone (mephedrone) and 4-Methylbuphedrone, and the p-methyl derivative of Pentedrone.

Chemistry[edit | edit source]

4-Methyl-α-ethylaminopentiophenone is a synthetic cathinone. Cathinones are structurally similar to amphetamines, they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional ethyl group attached to the alpha carbon. Cathinones such as 4-Methyl-α-ethylaminopentiophenone are alpha-methylated phenethylamines.

Pharmacology[edit | edit source]

The pharmacology of 4-Methyl-α-ethylaminopentiophenone is not well known. As a cathinone, it is presumed to act as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is likely to cause similar effects to mephedrone, but with a longer duration of action.

Effects[edit | edit source]

The effects of 4-Methyl-α-ethylaminopentiophenone can vary greatly depending on the dose and individual's physiology. Common effects reported by users include stimulation, euphoria, increased alertness and focus, and increased sociability. However, negative side effects can include anxiety, paranoia, insomnia, and heart problems.

Legal Status[edit | edit source]

The legal status of 4-Methyl-α-ethylaminopentiophenone varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned cathinones.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD