4-Methyl-α-ethylaminopentiophenone

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A synthetic stimulant drug of the cathinone class


4-Methyl-α-ethylaminopentiophenone (also known as 4-MEAP) is a synthetic stimulant drug of the cathinone class. It is chemically related to other synthetic cathinones such as mephedrone and methcathinone.

Chemical Structure and Properties[edit | edit source]

Chemical structure of 4-MEAP

4-MEAP is a derivative of α-pyrrolidinopentiophenone (α-PVP), with a methyl group added to the fourth position of the phenyl ring. Its chemical formula is C14H21NO, and it has a molecular weight of 219.32 g/mol. The presence of the ethylamino group in its structure is responsible for its stimulant effects.

Pharmacology[edit | edit source]

4-MEAP acts as a central nervous system stimulant. It is believed to exert its effects by increasing the levels of neurotransmitters such as dopamine and norepinephrine in the brain, similar to other cathinones. This increase in neurotransmitter levels leads to enhanced alertness, energy, and euphoria.

Effects and Usage[edit | edit source]

The effects of 4-MEAP are similar to those of other stimulant drugs. Users may experience increased energy, alertness, and sociability. However, it can also lead to adverse effects such as anxiety, paranoia, and increased heart rate. Due to its stimulant properties, 4-MEAP has been used recreationally, although it is not approved for medical use.

Legal Status[edit | edit source]

The legal status of 4-MEAP varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is important for users to be aware of the legal implications of possessing or distributing 4-MEAP in their region.

Safety and Toxicity[edit | edit source]

The safety profile of 4-MEAP is not well-established, and its use can be associated with significant risks. Potential adverse effects include cardiovascular issues, neurological disturbances, and psychological effects such as anxiety and paranoia. Long-term effects and the potential for addiction are not well understood.

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Contributors: Prab R. Tumpati, MD