4-Methylmethcathinone

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4-Methylmethcathinone


4-Methylmethcathinone (4-MMC), also known as mephedrone, is a psychoactive drug that is part of the amphetamine and cathinone chemical classes. It is known for its stimulant effects similar to those of MDMA (ecstasy) and cocaine. 4-MMC has gained popularity in the recreational drug scene, particularly in Europe, due to its euphoric and empathogenic effects. However, its legal status has changed in many countries due to concerns over health risks and potential for abuse.

Chemistry[edit | edit source]

4-Methylmethcathinone is a synthetic compound that belongs to the substituted cathinones, which are derived from the khat plant. Its chemical structure is closely related to that of ephedrine, a compound found in the khat plant, and methamphetamine.

Pharmacology[edit | edit source]

The pharmacological action of 4-MMC involves increasing the release of neurotransmitters such as dopamine, serotonin, and norepinephrine in the brain, leading to its stimulant and euphoric effects. The compound acts as a reuptake inhibitor and releasing agent for these neurotransmitters, which enhances their activity in the central nervous system.

Effects[edit | edit source]

Users of 4-Methylmethcathinone report effects that include euphoria, increased energy, enhanced sociability, and heightened sensory perception. However, adverse effects are also reported and can include anxiety, paranoia, tachycardia (increased heart rate), hypertension (high blood pressure), and in severe cases, overdose leading to death.

Legal Status[edit | edit source]

The legal status of 4-MMC varies by country. It has been classified as a controlled substance in many countries, including the United States, Canada, Australia, and several European nations, due to its potential for abuse and harm.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD