5F-EMB-PINACA

5F-EMB-PINACA is a carbamate synthetic cannabinoid that has been found as an ingredient in products sold as herbal smoking blends. This compound was first identified in Japan in 2014. It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.58 nM and 0.44 nM, respectively.

Chemistry

5F-EMB-PINACA is a carbamate synthetic cannabinoid that is structurally related to AB-PINACA. It has a fluorine atom at the 5-position of the indazole ring. The carbamate group in 5F-EMB-PINACA is located at the nitrogen atom of the indazole ring, which is a unique structural feature among synthetic cannabinoids.

Pharmacology

5F-EMB-PINACA acts as a potent agonist for the CB1 and CB2 receptors. The EC50 values for these receptors are 0.58 nM and 0.44 nM, respectively. The exact mechanism of action of 5F-EMB-PINACA is not fully understood, but it is believed to mimic the effects of naturally occurring cannabinoids by activating these receptors.

Effects

The effects of 5F-EMB-PINACA can vary greatly depending on the dose and the individual's tolerance to cannabinoids. Some reported effects include euphoria, relaxation, altered perception, and psychosis in some cases. Due to its potency and the lack of knowledge about its safety profile, 5F-EMB-PINACA poses significant risks to users.

Legal Status

The legal status of 5F-EMB-PINACA varies by country and state. In the United States, it is a Schedule I controlled substance. In the European Union, it is a controlled substance under the Psychoactive Substances Act.

See Also

• Synthetic cannabinoids
• AB-PINACA
• Indazole
• Cannabinoid receptor

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