6-Nitroquipazine

6-Nitroquipazine is a quinoline derivative and a potent and selective inhibitor of the serotonin transporter (SERT). It is used in scientific research to study the role of the SERT in the brain.

Chemistry

6-Nitroquipazine is a derivative of the quinoline class of compounds. It has a nitro group at the 6 position of the quinoline ring, hence its name. The quinoline ring is a heterocyclic aromatic organic compound that consists of a benzene ring fused to a pyridine ring.

Pharmacology

6-Nitroquipazine acts as a potent and selective inhibitor of the serotonin transporter (SERT). This means it can block the reuptake of the neurotransmitter serotonin, leading to increased levels of serotonin in the synaptic cleft. This can result in increased serotonergic neurotransmission.

Uses in Research

Due to its potent and selective inhibition of the SERT, 6-Nitroquipazine is used in scientific research to study the role of the SERT in the brain. It can be used to investigate the effects of increased serotonergic neurotransmission, and to study disorders that are thought to be related to dysregulation of the serotonergic system, such as depression and anxiety disorders.

See Also

• Serotonin transporter
• Quinoline
• Neurotransmitter serotonin
• Depression
• Anxiety disorders

6-Nitroquipazine Resources
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