60S ribosomal protein L10

Ideogram human chromosome X

60S ribosomal protein L10

60S ribosomal protein L10 is a protein that in humans is encoded by the RPL10 gene. It is a component of the large subunit of the ribosome and plays a crucial role in protein synthesis. This protein is essential for the proper functioning of the ribosome and is highly conserved across species.

Structure

60S ribosomal protein L10 is a ribosomal protein that is part of the large subunit of the ribosome. It consists of a single polypeptide chain and contains specific structural motifs that are important for its function in protein synthesis.

Function

As a component of the ribosome, 60S ribosomal protein L10 plays a key role in the translation of messenger RNA (mRNA) into protein. It is involved in the formation of peptide bonds between amino acids during protein synthesis. This protein is essential for the accurate and efficient translation of genetic information into functional proteins.

Clinical Significance

Mutations in the RPL10 gene, which encodes 60S ribosomal protein L10, have been associated with various human diseases. These mutations can disrupt the normal function of the ribosome and lead to defects in protein synthesis. Dysregulation of ribosomal proteins like L10 has been linked to conditions such as Diamond-Blackfan anemia and cancer.