ANKRD2

Ideogram human chromosome 10

ANKRD2

ANKRD2 is a gene that encodes a protein known as Ankyrin Repeat Domain 2. This protein is involved in various cellular processes, including gene regulation, protein-protein interactions, and signal transduction.

Structure

The ANKRD2 gene is located on chromosome 4 in humans. It consists of multiple exons that encode the Ankyrin Repeat Domain 2 protein. This protein contains several ankyrin repeat domains, which are protein motifs that are involved in mediating protein-protein interactions.

Function

The Ankyrin Repeat Domain 2 protein plays a role in regulating gene expression by interacting with other proteins and DNA. It is also involved in cellular signaling pathways and may have functions in cell growth and differentiation.

Clinical Significance

Mutations in the ANKRD2 gene have been associated with certain diseases, including cardiac disorders and muscular dystrophy. Understanding the function of this gene and its protein product is important for elucidating the underlying mechanisms of these conditions.

Interactions

The Ankyrin Repeat Domain 2 protein has been shown to interact with various other proteins in the cell, including transcription factors and signaling molecules. These interactions are crucial for its role in gene regulation and signal transduction.