ANXA8L2

Ideogram human chromosome 10

ANXA8L2

ANXA8L2 is a gene that encodes a member of the annexin family of calcium-dependent phospholipid-binding proteins. This gene is located on chromosome 10 in humans and is involved in various cellular processes.

Function

The protein encoded by ANXA8L2 is thought to play a role in the regulation of membrane organization and dynamics. It may also be involved in intracellular signaling pathways and cell growth.

Structure

ANXA8L2 belongs to the annexin family, which are characterized by their ability to bind to phospholipids in a calcium-dependent manner. The protein structure consists of four annexin repeats, each containing a conserved calcium-binding site.

Expression

ANXA8L2 is expressed in a variety of tissues, with higher levels found in certain organs such as the brain and liver. Its expression pattern suggests a role in tissue-specific functions.

Clinical Significance

Mutations in the ANXA8L2 gene have been associated with certain diseases, although the exact mechanisms are still being investigated. Further research is needed to fully understand the implications of these genetic variations.

Interactions

ANXA8L2 has been shown to interact with other proteins involved in cellular signaling and membrane trafficking. These interactions may modulate its function and contribute to its role in various cellular processes.