AR-C 66096

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AR-C 66096 is a chemical compound that has been studied for its potential pharmacological effects, particularly as an antagonist of the P2Y12 receptor. This receptor is a member of the P2Y receptor family, which are G protein-coupled receptors (GPCRs) involved in various physiological processes, including platelet aggregation.

Pharmacology[edit | edit source]

AR-C 66096 functions primarily as a selective antagonist of the P2Y12 receptor. The P2Y12 receptor is predominantly expressed on the surface of platelets, where it plays a crucial role in the regulation of platelet activation and aggregation. By inhibiting this receptor, AR-C 66096 can potentially reduce platelet aggregation, which is a key factor in the formation of thrombi.

Mechanism of Action[edit | edit source]

The mechanism of action of AR-C 66096 involves the blockade of the P2Y12 receptor, which is activated by adenosine diphosphate (ADP). ADP is a potent inducer of platelet aggregation, and its effects are mediated through the P2Y12 receptor. By antagonizing this receptor, AR-C 66096 prevents ADP from binding, thereby inhibiting the downstream signaling pathways that lead to platelet activation.

Potential Applications[edit | edit source]

Due to its ability to inhibit platelet aggregation, AR-C 66096 has been investigated for its potential use in the prevention of thrombotic disorders, such as myocardial infarction and stroke. However, as of the latest research, AR-C 66096 remains a research chemical and has not been approved for clinical use.

Research and Development[edit | edit source]

Research on AR-C 66096 has primarily focused on its pharmacological properties and potential therapeutic applications. Studies have demonstrated its efficacy in inhibiting platelet aggregation in vitro and in animal models. However, further research is needed to fully understand its pharmacokinetics, safety profile, and potential side effects in humans.

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