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ARL2

From WikiMD's Wellness Encyclopedia

Protein ARL2 PDB 1ksg

ARL2

ARL2 is a gene that encodes a small GTPase protein involved in various cellular processes. It is located on chromosome 11 in humans. The protein encoded by ARL2 is a member of the ADP-ribosylation factor-like protein family.

Function[edit | edit source]

The ARL2 protein plays a role in intracellular vesicular trafficking and cytoskeleton organization. It is known to interact with other proteins such as BART and UNC119. ARL2 is also implicated in ciliary function and microtubule dynamics.

Clinical Significance[edit | edit source]

Mutations in the ARL2 gene have been associated with certain genetic disorders and diseases. Research suggests that dysregulation of ARL2 expression may contribute to the pathogenesis of certain cancers and neurodegenerative disorders.

Interactions[edit | edit source]

ARL2 has been shown to interact with several proteins involved in cellular processes. These interactions are crucial for the proper functioning of ARL2 within the cell.

References[edit | edit source]