Acceptable Risk (novel)

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Acceptable Risk

Acceptable Risk is a novel written by Robin Cook, a renowned author known for his work in the medical thriller genre. The book was published in 1994 and explores the themes of medical ethics, the nature of human behavior, and the quest for scientific advancement at the potential cost of human lives. The story is set against the backdrop of the pharmaceutical industry and its relentless pursuit of new medications, highlighting the moral dilemmas that arise when the line between beneficial medicine and dangerous drugs becomes blurred.

Plot Summary[edit | edit source]

The novel follows the story of Edward Armstrong, a brilliant but unorthodox researcher who stumbles upon a groundbreaking discovery in the field of psychopharmacology. Armstrong's research leads him to a mold found in the basement of an old mill in Massachusetts, which has the potential to be developed into a revolutionary new antidepressant. As the story unfolds, the protagonist becomes entangled in a web of corporate greed, scientific ambition, and ethical quandaries. The narrative delves into the history of the mill, revealing its connection to the Salem witch trials and suggesting that the mold may have played a role in the historical events.

As Armstrong progresses with his research, he faces increasing pressure from his corporate sponsors who are eager to capitalize on the new drug. The novel raises questions about the acceptable risk associated with pharmaceutical development, especially when the side effects of the new drug begin to manifest in alarming ways. The ethical implications of sacrificing a few for the benefit of many are explored through the characters' decisions and the consequences they face.

Themes and Analysis[edit | edit source]

Acceptable Risk addresses several key themes, including the ethical considerations in medical research, the influence of corporate interests on scientific discovery, and the historical context of drug development. Cook uses the narrative to critique the pharmaceutical industry's often aggressive pursuit of profit, sometimes at the expense of patient safety. The novel also touches on the idea of human experimentation and the moral responsibility of scientists to ensure the well-being of their subjects.

The historical connection to the Salem witch trials adds a layer of complexity to the story, suggesting that the pursuit of knowledge and the fear of the unknown have always been intertwined with human behavior. This historical parallel serves as a cautionary tale about the dangers of unchecked ambition and the potential consequences of manipulating nature for personal gain.

Reception[edit | edit source]

Acceptable Risk received mixed reviews from critics. Some praised Cook's ability to weave together medical science, history, and ethical dilemmas into a compelling narrative, while others criticized the novel for its sometimes-predictable plot and lack of character development. Despite the criticisms, the book was a commercial success and further established Robin Cook as a leading figure in the medical thriller genre.

See Also[edit | edit source]

Contributors: Prab R. Tumpati, MD