Acetylglycinamide chloral hydrate
Acetylglycinamide chloral hydrate (ACH) is a chemical compound with the molecular formula C4H7Cl3N2O3. It is a derivative of chloral hydrate and glycinamide, and is used in various chemical synthesis processes.
Chemical Structure[edit | edit source]
The chemical structure of acetylglycinamide chloral hydrate consists of a chloral group attached to a glycinamide group via an acetyl linkage. This structure gives ACH its unique chemical properties, including its reactivity and solubility.
Synthesis[edit | edit source]
Acetylglycinamide chloral hydrate is synthesized through a reaction between chloral hydrate and glycinamide. The reaction is typically carried out in an organic solvent such as dichloromethane or ethyl acetate, and may be catalyzed by an acid or base.
Properties[edit | edit source]
ACH is a white, crystalline solid at room temperature. It is soluble in water and most organic solvents. It has a melting point of approximately 150-155 degrees Celsius.
Applications[edit | edit source]
Acetylglycinamide chloral hydrate is primarily used in chemical synthesis. It is a versatile reagent that can be used in a variety of reactions, including condensation reactions, addition reactions, and substitution reactions. It is also used in the synthesis of certain pharmaceuticals and biologically active compounds.
Safety[edit | edit source]
Like many chemical compounds, ACH should be handled with care. It can cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled. Appropriate safety measures should be taken when handling this compound.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD