Adult stem cell

From WikiMD.com Medical Encyclopedia

Adult Stem Cell[edit | edit source]

Adult stem cells, also known as somatic stem cells, are undifferentiated cells found throughout the body after development. They multiply by cell division to replenish dying cells and regenerate damaged tissues. Unlike embryonic stem cells, adult stem cells are not controversial because they are derived from adult tissue samples rather than destroyed embryos.

Characteristics[edit | edit source]

Adult stem cells are characterized by their ability to self-renew and differentiate into specialized cell types. They are multipotent, meaning they can give rise to a limited range of cell types related to their tissue of origin. For example, hematopoietic stem cells in the bone marrow can differentiate into various blood cells, while mesenchymal stem cells can become bone, cartilage, or fat cells.

Sources[edit | edit source]

Adult stem cells can be found in various tissues throughout the body, including:

These cells are typically present in small numbers and are difficult to isolate and grow in culture.

Function[edit | edit source]

The primary role of adult stem cells is to maintain and repair the tissue in which they are found. They are crucial for the body's natural healing processes. For instance, hematopoietic stem cells continuously replenish the blood supply, while epithelial stem cells in the skin and gut maintain the integrity of these tissues.

Clinical Applications[edit | edit source]

Adult stem cells have been used in various clinical applications, particularly in the field of regenerative medicine. Some of the notable applications include:

  • Bone marrow transplantation for treating blood disorders such as leukemia and lymphoma.
  • Regeneration of damaged tissues, such as cartilage repair in osteoarthritis.
  • Potential treatments for neurodegenerative diseases like Parkinson's disease and spinal cord injuries.

Challenges[edit | edit source]

Despite their potential, there are several challenges associated with the use of adult stem cells:

  • Limited differentiation potential compared to embryonic stem cells.
  • Difficulty in isolating and expanding these cells in vitro.
  • Risk of immune rejection if donor cells are used.

Images[edit | edit source]

Mesenchymal stem cells under high magnification.
Diagram of stem cell division and differentiation.

Related Pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD