Affitin

From WikiMD's Wellness Encyclopedia

Affitin[edit | edit source]

The molecular structure of an Affitin molecule

Affitin refers to a type of protein binder derived from the albumin-binding domain of streptococcal protein G. Due to their small size, high stability, and adaptability, Affitins are being researched for various therapeutic and diagnostic applications.

Characteristics[edit | edit source]

Affitins have several notable properties that make them of interest in the field of biomedicine:

  • Size: They are smaller than antibodies, making them more accessible to certain molecular targets.
  • Stability: Affitins are resistant to chemical and thermal denaturation.
  • Versatility: They can be engineered to bind to a wide variety of targets with high specificity and affinity.

Applications[edit | edit source]

Affitins are being explored for several potential applications:

  • Therapeutics: As potential alternatives or adjuncts to traditional antibodies in targeted therapy.
  • Diagnostics: Due to their ability to bind specific targets, they can be used in diagnostic assays.
  • Research tools: Used in the study of protein-protein interactions and other molecular biology applications.

Production[edit | edit source]

Affitins are usually produced through bacterial expression systems, followed by purification processes.

See Also[edit | edit source]

References[edit | edit source]

Contributors: Prab R. Tumpati, MD