Affitin

Affitin

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The molecular structure of an Affitin molecule

Affitin refers to a type of protein binder derived from the albumin-binding domain of streptococcal protein G. Due to their small size, high stability, and adaptability, Affitins are being researched for various therapeutic and diagnostic applications.

Characteristics

Affitins have several notable properties that make them of interest in the field of biomedicine:

• Size: They are smaller than antibodies, making them more accessible to certain molecular targets.
• Stability: Affitins are resistant to chemical and thermal denaturation.
• Versatility: They can be engineered to bind to a wide variety of targets with high specificity and affinity.

Applications

Affitins are being explored for several potential applications:

• Therapeutics: As potential alternatives or adjuncts to traditional antibodies in targeted therapy.
• Diagnostics: Due to their ability to bind specific targets, they can be used in diagnostic assays.
• Research tools: Used in the study of protein-protein interactions and other molecular biology applications.

Production

Affitins are usually produced through bacterial expression systems, followed by purification processes.

See Also

• Antibody
• Protein engineering

References

• "Affitins as a suitable alternative to antibodies" - Journal of Molecular Biology.
• "The structure and potential therapeutic applications of Affitins" - Nature Biotechnology.